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Promethazine has an elimination 50 %-life of 10-14 hrs, with excretion of metabolites showing while in the urine and feces. The sulfoxides of promethazine and N-demethylpromethazine will be the predominant metabolites showing while in the urine.The phenylephrine contained in Promethazine VC with Codeine Oral Answer can create cardiovascular and cen